A stomach ulcer can be caused by a variety of factors

Helicobacter pylori - these bacteria is thought to be responsible for around 60 per cent of stomach ulcers and at least 90 per cent of duodenal ulcers.
Certain medications - including aspirin, taken regularly to help prevent heart attack or stroke, and drugs for arthritis. Anti-inflammatory medications (NSAIDS) are thought to cause around two fifths of stomach ulcers.
Cancer - stomach cancer can present as an ulcer, particularly in older people.

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